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Table 3 The association between quintiles of whole blood mercury and blood pressure parameters among Inuit § (30–69 years) in Greenland, the analyses are adjusted for confounders ab

From: The association between blood pressure and whole blood methylmercury in a cross-sectional study among Inuit in Greenland

 

Log-systolic blood pressure*

 

Log-diastolic blood pressure*

 

Log-pulse pressure*

 

Whole blood mercury (μg/L)

(exp)Parameter estimate (95% CI)

Pc (Pd)

(exp)Parameter estimate (95% CI)

Pc (Pd)

(exp)Parameter estimate (95% CI)

Pc (Pd)

Men

      

Quintile 1 (range: 0.4-8.7)

1

(0.45)

1

(0.01)

1

(0.51)

Quintile 2 (range: 8.8-17.0)

1.00 (0.97-1.03)

0.87

1.00 (0.96-1.03)

0.86

0.99 (0.94-1.05)

0.80

Quintile 3 (range: 17.3-26.1)

0.98 (0.94-1.01)

0.17

0.97 (0.93-1.01)

0.12

0.98 (0.92-1.04)

0.50

Quintile 4 (range: 27.0-49.0)

0.98 (0.94-1.01)

0.19

0.94 (0.90-0.98)

0.007

1.02 (0.96-1.09)

0.52

Quintile 5 (range: 50.0-280.0)

0.97 (0.93-1.01)

0.15

0.93 (0.89-0.98)

0.004

1.03 (0.96-1.11)

0.38

Women

      

Quintile 1 (range: 0.05-6.4)

1

(0.17)

1

(0.19)

1

(0.01)

Quintile 2 (range: 6.6-12.0)

0.99 (0.97-1.02)

0.69

1.01 (0.98-1.04)

0.70

0.97 (0.93-1.03)

0.33

Quintile 3 (range: 12.2-20.1)

0.98 (0.96-1.01)

0.26

1.01 (0.97-1.04)

0.71

0.94 (0.89-0.997)

0.04

Quintile 4 (range: 21.0-35.0)

1.02 (0.99-1.05)

0.30

1.00 (0.97-1.04)

0.94

1.03 (0.97-1.10)

0.32

Quintile 5 (range: 36.0-170.0)

0.99 (0.95-1.02)

0.52

0.97 (0.93-1.01)

0.11

1.02 (0.95-1.10)

0.55

  1. § Only participants with four Greenlandic grandparents and with no anti-hypertensive drug therapy.
  2. a Confounders: age, smoking habits, blood selenium, ratio of n-3/n-6 fatty acids, waist circumference.
  3. b The models were based on 615 men and 787 women (with non-missing values for all included variables).
  4. c The outcome variables of interest, systolic and diastolic BP, and pulse pressure, were not normally distributed and were included as natural log-transformed variables in the model. The parameter estimate is presented as the antilog of the result of the linear regression analyses.
  5. d P-value of a “pairwise” comparison with the first quintile of whole blood mercury.
  6. e P-value of a Wald-test for the overall effect of mercury on blood pressure and pulse pressure.