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Table 2 Association between exposure to paint fumes in the residence during 1st trimester of pregnancy and congential anomalies among 19935 women and child pairs from the Danish National Birth Cohort

From: Non-occupational exposure to paint fumes during pregnancy and risk of congenital anomalies: a cohort study

 

Cases

Non-cases

Crude

Adjusted*

 

N

N

OR (95 % CI)

OR (95 % CI)

All congenital malformation

 Not exposed

1013

17518

1.00 (Ref)

1.00 (Ref)

 Exposed

73

1331

0.95 (0.74-1.21)

0.95 (0.74-1.21)

Nervous system

 Not exposed

24

18507

1.00 (Ref)

1.00 (Ref)

 Exposed

4

1400

2.20 (0.76-6.36)

2.19 (0.76-6.32)

Eye

 Not exposed

37

18494

1.00 (Ref)

1.00 (Ref)

 Exposed

5

1399

1.79 (0.70-4.55)

1.79 (0.70-4.57)

Ear, face and neck

 Not exposed

31

18500

1.00 (Ref)

1.00 (Ref)

 Exposed

5

1399

2.13 (0.83-5.49)

2.15 (0.84-5.55)

Congenital heart defects

 Not exposed

156

18375

1.00 (Ref)

1.00 (Ref)

 Exposed

9

1395

0.76 (0.39-1.49)

0.76 (0.39-1.49)

Respiratory system

 Not exposed

23

18508

1.00 (Ref)

1.00 (Ref)

 Exposed

2

1402

0.27 - 4.87

1.13 (0.27-4.79)

Cleft lip and cleft palate

 Not exposed

36

18495

1.00 (Ref)

1.00 (Ref)

 Exposed

3

1401

1.10 (0.34-3.58)

1.06 (0.33-3.46)

Digestive system

 Not exposed

44

18487

1.00 (Ref)

1.00 (Ref)

 Exposed

2

1402

0.60 (0.15-2.48)

0.61 (0.15-2.50)

Abdominal wall defects

 Not exposed

10

18521

1.00 (Ref)

1.00 (Ref)

 Exposed

0

1404

  

Renal

 Not exposed

50

18481

1.00 (Ref)

1.00 (Ref)

 Exposed

8

1396

2.12 (1.00-4.48)

2.16 (1.02-4.58)

Genital

 Not exposed

220

18311

1.00 (Ref)

1.00 (Ref)

 Exposed

14

1390

0.84 (0.49-1.44)

0.83 (0.48-1.43)

Limb defects

 Not exposed

386

18145

1.00 (Ref)

1.00 (Ref)

 Exposed

24

1380

0.82 (0.54-1.24)

0.82 (0.54-1.24)

Muscula and skeletal

 Not exposed

45

18486

1.00 (Ref)

1.00 (Ref)

 Exposed

6

1398

1.76 (0.75-4.14)

1.77 (0.75-4.16)

Other malformation

 Not exposed

96

18435

1.00 (Ref)

1.00 (Ref)

 Exposed

9

1395

1.24 (0.62-2.46)

1.24 (0.62-2.46)

  1. *Adjusted for: Maternal age, smoking during 1st trimester, alcohol consumption during 1st trimester, working with organic solvents at first interview (12th week).