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Table 2 Relationships of endogenous hormones with diabetes in men, n = 63 a

From: Polychlorinated biphenyl exposure, diabetes and endogenous hormones: a cross-sectional study in men previously employed at a capacitor manufacturing plant

 

Meansb

Odds Ratiosc(95% CIs)

Endogenous hormone

With diabetesd

Without diabetes

P-value

Controlling for age, BMI group and total lipids

TSH ultra sens in μIU/mLe

1.4

1.7

.192

0.3 (0.1, 2.0)

Triiodothyronine in ng/dLe

121.8

124.3

.693

0.1 (0.0, 118.9)

T3-uptake in%

29.6

31.2

.261

0.9 (0.7, 1.1)

Total T4 in μg/dLe

7.9

7.3

.238

17.8 (0.1, >999.9)

Free T4 Indexe

2.3

2.3

.760

1.7 (0.0, 319.9)

SHBG in nmol/Le

33.5

40.8

.427

0.5 (0.1, 2.5)

LH in mIU/mle

4.2

4.8

.490

0.6 (0.1, 2.5)

Testosterone (T)e

17.8

19.6

.539

0.8 (0.1, 7.0)

% T bound to SHBG

29.6

30.1

.860

1.0 (0.8, 1.1)

Conc. T bound to SHBGe

5.1

5.7

.575

0.8 (0.1, 4.3)

Estradiol (E2) in pmol/Le

143.7

126.7

.267

7.0 (0.3, 153.7)

DHEA Sulfate in μmol/Le

7.1

5.4

.463

2.1 (0.6, 7.9)

Cortisol in nmol/Le

631.9

507.8

.191

5.1 (0.6, 46.9)

2-OHE1 in ng/mLe

4.7

7.2

.063

0.2 (0.0, 1.2)

16a-OHE1 in ng/mLe

2.9

5.0

.024

0.1 (0.0, 0.8)

2-OHE1/16a-OHE1e

1.5

1.5

.895

1.3 (0.2, 10.2)

2-OHE1/Creatininee

5.6

5.2

.759

1.5 (0.3, 7.2)

16a-OHE1/Creatininee

3.7

3.6

.959

1.2 (0.2, 7.0)

  1. a Hormones treated as continuous variables and analyzed with and without control for age, BMI group, and total lipids in logistic regression.
  2. bGeometric mean presented for those variables natural log-transformed.
  3. cAdjusted odds ratio controls for age, BMI group, and total lipids.
  4. dA total of 7 men had diagnosed diabetes and 56 men were without a diagnosis of diabetes.
  5. eVariable not normally distributed, therefore natural log-transformed variable used in logistic regression model.