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Table 2 Benchmark results for postnatal PFC exposure (in terms of serum concentrations in ng/mL measured at 5 years) with vaccine antibody concentrations at 7 years as the outcomes

From: Immunotoxicity of perfluorinated alkylates: calculation of benchmark doses based on serum concentrations in children

   

BMR = 5%

BMR = 10%

Fit (−2log(L))

Outcome

Exposure

Model*

BMD

BMDL

BMD

BMDL

Full scale

Low dose

Tetanus

PFOS

Linear

2.70

1.31

5.55

2.69

1719.81

313.78

  

Log

0.13

0.07

0.29

0.14

1719.30

313.75

  

Piecewise

1.45

0.56

2.98

1.16

1719.54

313.54

 

PFOA

Linear

0.38

0.25

0.77

0.51

1712.43

391.53

  

Log

0.07

0.04

0.14

0.09

1712.88

391.63

  

Piecewise

0.52

0.16

1.07

0.34

1712.33

391.64

Diphtheria

PFOS

Linear

2.30

1.25

4.72

2.57

1656.86

314.00

  

Log

0.11

0.06

0.24

0.13

1655.96

313.38

  

Piecewise

0.98

0.49

2.01

1.01

1655.77

313.10

 

PFOA

Linear

0.59

0.33

1.21

0.68

1656.15

362.37

  

Log

0.10

0.06

0.22

0.12

1656.14

362.39

  

Piecewise

0.48

0.17

0.99

0.34

1656.12

362.30

  1. *K-power model was identical to the linear model.
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Environmental Health

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