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Table 3 Results of sensitivity analyses using low-dose threshold models with no effect below the lowest observed exposures

From: Immunotoxicity of perfluorinated alkylates: calculation of benchmark doses based on serum concentrations in children

  

BMR = 5%

BMR = 10%

Outcome/Exposure

Model

BMD

BMDL

BMD

BMDL

Diphtheria/PFOS

Linear

8.48

7.43

10.90

8.75

 

Log

6.96

6.62

7.89

7.11

 

Piecewise

7.16

6.67

8.19

7.19

Tetanus/PFOA

Linear

1.70

1.57

2.10

1.83

 

Log

1.48

1.43

1.65

1.53

 

Piecewise

1.85

1.49

2.40

1.66

  1. Benchmark results for serum concentrations (in ng/mL) measured at 5 years in regard to vaccine antibody concentrations at 7 years. Results are given for the exposures and outcomes showing the lowest results in Table 1.