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Table 4 Summary of cohort studies on NO 2 and mortality from all causes and cardiovascular diseases (excess risk per 10 μg/m 3 )

From: Long-term air pollution exposure and cardio- respiratory mortality: a review

Study name

Study population

Follow-up period

Pollutant

Conca(μg/m3)

Spatial scaleb

% change in risk (95% CI) in mortality per 10 μg/m3

References

      

All causes

Cardiovascular

 

Oslo cohort

16,209 men in Oslo, Norway

1972 – 1998

NOx

11 (1 – 168)

Address (DISP)

8 (6,11)

NA

[68]

Netherlands Cohort Study

120, 852 subjects from Netherlands

1987 -1996

NO2

37 (15–67)

Address (LUR)

8 (0, 16)

7 (−6, 21)

[23]

German cohort

4752 women in Ruhr and surrounding area

1985 – 2003

NO2

39 (20 – 60)

Address (near)

11 (1,21)

36 (14, 63)

[20]

German cohort

4752 women in Ruhr and surrounding area

1985 – 2008

NO2

39 (20 – 60)

Address (near)

11 (4,18)

32 (18, 47)

[21]

PAARC

14,284 adults in 24 French areas

1974 – 1998

NO2

20 (12 – 32)

Address (near)

14 (3, 25)

27 (4, 56)

[42]

China nat. hypertension survey

70,497 men and women

1991 - 2000

NOx

50 (20 – 122)

City

2 (0, 3)

2 (1, 4)

[31]

Vancouver cohort

452,735 Vancouver residents aged 45–85 yr

1999 – 2002

NO2

32 (15 – 58)

Address (LUR)

NA

5 (1, 9)

[30]

DCH

52,061 adults in Copenhagen and Arhus

1993 - 2009

NO2

17 (11 – 60)

Address (DISP)

8 (2, 13)

15 (3,27)

[69]

US trucking industry cohort

53,814 men in the US trucking industry

1985 -2000

NO2

28 (14)

Address (LUR)

5 (3, 7)

4 (0, 8)

[32]

Chinese retrospective cohort study

9,941 adults from five districts of Shenyang city

1998 -2009

NO2

46 (18–78)

District (mean)

145 (134, 158)

146 (131, 163)

[33]

Rome longitudinal study

684,000 adults from Rome

2001 - 2006

NO2

45 (11)

Address (LUR)

4 (3, 5)

NA

[56]

California Teachers study

101,784 female teachers

1997 -2005

NO2

67 (10 – 134)

Address (Inter)

−3 (−9, 4)

−2 (−12, 9)

[36]

Shizuoka elderly cohort

13,444 adults > 65 yr

1999 - 2006

NO2

25 (−19, 75)

Address (LUR)

2 (−4, 8)

15 (3, 28)

[70]

Ontario tax cohort

205, 440 adults in Toronto, Hamilton,Windsor

1982 – 2004

NO2

43 (8), 31 (6), 24 (5)c

Address (LUR)

NA

8 (5, 11)

[71]

Rome longitudinal study

1,265,058 adults from Rome

2001 - 2010

NO2

44 (13–75)

Address (LUR)

3 (2, 3)

3 (2, 4)

[38]

  1. a Mean with minimum – maximum in parentheses (μg/m3). One number in parentheses is standard deviation.
  2. b Spatial scale of exposure assignment, in parentheses exposure assignment method. City = average of monitors within the city; Near = nearest monitor concentration; LUR = land use regression; Disp = dispersion modeling; Inter = interpolation.
  3. c Mean (IQR) per city.
  4. Studies adjusted for individual smoking except references [26, 28, 30, 34, 38, 56].