Table 4 Infertility odds ratios according to female serum concentrations of PFAS
From: Perfluoroalkyl substances and time to pregnancy in couples from Greenland, Poland and Ukraine
N | PFOA | PFOS | PFHxS | PFNA | |||||
|---|---|---|---|---|---|---|---|---|---|
Greenland | n | OR (95% CI) | n | OR (95% CI) | n | OR (95% CI) | n | OR (95% CI) | |
Low | 150 | 18 | 1 (Reference) | 14 | 1 (Reference) | 20 | 1 (Reference) | 12 | 1 (Reference) |
Medium | 149 | 22 | 1.30 (0.66, 2.54) | 23 | 1.73 (0.85, 3.49) | 18 | 0.90 (0.45, 1.76) | 23 | 1.95 (0.95, 3.99) |
High | 149 | 22 | 1.57 (0.76, 3.25) | 25 | 1.82 (0.90, 3.67) | 24 | 1.22 (0.64, 2.36) | 27 | 2.15 (1.05, 4.42) |
Continuous log-scale | 448 | 62 | 1.20 (0.61, 2.37) | 62 | 1.74 (0.97, 3.13) | 62 | 0.99 (0.59, 1.65) | 62 | 1.97 (1.22, 3.19) |
Poland | |||||||||
Low | 68 | 10 | 1 (Reference) | 7 | 1 (Reference) | 10 | 1 (Reference) | 13 | 1 (Reference) |
Medium | 68 | 12 | 1.25 (0.50, 3.13) | 13 | 1.93 (0.72, 5.18) | 13 | 1.52 (0.60, 3.84) | 11 | 0.92 (0.38, 2.22) |
High | 67 | 11 | 1.41 (0.55, 3.61) | 13 | 1.92 (0.72, 5.14) | 10 | 1.07 (0.41, 2.80) | 9 | 0.65 (0.26, 1.66) |
Continuous log-scale | 203 | 33 | 1.11 (0.44, 2.80) | 33 | 2.06 (0.69, 6.12) | 33 | 1.05 (0.50, 2.20) | 33 | 0.74 (0.32, 1.72) |
Ukraine | |||||||||
Low | 96 | 19 | 1 (Reference) | 18 | 1 (Reference) | 17 | 1 (Reference) | 16 | 1 (Reference) |
Medium | 96 | 16 | 0.66 (0.30, 1.45) | 20 | 1.51 (0.70, 3.26) | 26 | 1.37 (0.66, 2.85) | 22 | 1.39 (0.65, 2.97) |
High | 95 | 23 | 1.21 (0.57, 2.58) | 20 | 1.22 (0.56, 2.65) | 15 | 0.61 (0.27, 1.38) | 20 | 1.17 (0.54, 2.53) |
Continuous log-scale | 287 | 58 | 0.79 (0.40, 1.54) | 58 | 0.77 (0.41, 1.43) | 58 | 0.76 (0.47, 1.24) | 58 | 1.26 (0.66, 2.40) |
Pooled sample | |||||||||
Continuous log-scale | 938 | 153 | 1.11 (0.74, 1.66) | 153 | 1.39 (0.93, 2.07) | 153 | 0.99 (0.73, 1.33) | 153 | 1.53 (1.08, 2.15) |