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Table 5 Hazard ratios (95% CI) for tertiles of maximum cumulative exposure and coefficients (95% CI) for continuous cumulative exposure (μg/L-year)

From: Mortality study of civilian employees exposed to contaminated drinking water at USMC Base Camp Lejeune: a retrospective cohort study

a. Leukemias (N = 12)

Contaminant

Medium Exposure

High Exposure

Cumulative Exposure

Log10 Cumulative Exposure

PCE

1.00 (0.14, 7.39) N = 2

1.82 (0.36, 9.32) N = 8

0.0010 (−0.0080, 0.0101) p = .82

−0.0498 (−0.7053, 0.6056) p = .88

TCE

0.94 (0.13, 6.97) N = 2

1.65 (0.32, 8.49) N = 8

<0.00001 (−0.0004, 0.0004) p = .84

−0.1712 (−0.6390, 0.2966) p = .47

Vinyl Chloride

1.01 (0.14, 7.45) N = 2

1.72 (0.33, 8.83) N = 8

0.0008 (−0.0051, 0.0067) p = .80

−0.0982 (−0.7363, 0.5398) p = .76

Benzene

0.36 (0.04, 3.52) N = 1

1.25 (0.31, 5.10) N = 8

0.0043 (−0.0206, 0.0292) p = .73

−0.1221 (−0.9360, 0.6918) p = .77

TVOC

0.94 (0.13, 6.97) N = 2

1.68 (0.33, 8.67) N = 8

<0.00001 (−0.0002, 0.0003) p = .83

−0.2334 (−0.7150, 0.2483) p = .34

b. Prostate Cancer (N = 10)

Contaminant

Medium Exposure

High Exposure

Cumulative Exposure

Log10 Cumulative Exposure

PCE

3.46 (0.38, 31.65) N = 4

2.08 (0.23, 18.91) N = 5

0.0039 (−0.0059, 0.0137) p = .44

0.3618 (−0.4945, 1.2181) p = .41

TCE

2.55 (0.26, 25.15) N = 3

2.39 (0.27, 21.14) N = 6

0.0002 (−0.0002, 0.0006) p = .37

0.4394 (−0.4270, 1.3058) p = .32

Vinyl Chloride

3.54 (0.39, 32.37) N = 4

2.00 (0.22, 18.21) N = 5

0.0023 (−0.0042, 0.0088) p = .49

0.3317 (−0.5040, 1.1674) p = .44

Benzene

1.60 (0.26, 9.79) N = 3

1.13 (0.21, 6.19) N = 5

0.0083 (−0.0188, 0.0354) p = .55

0.2962 (−0.6663, 1.2587) p = .55

TVOC

2.65 (0.27, 26.15) N = 3

2.47 (0.28, 21.82) N = 6

0.0001 (−0.0001, 0.0003) p = .39

0.4298 (−0.4438, 1.3034) p = .33

  1. Exposure lagged 10 years. Adjusted by sex, race, occupation (blue collar vs white collar) and education. Selected causes of death. Camp Lejeune cohort (N = 4,647). Reference group consists of Camp Lejeune civilian employees in the lowest tertile level of maximum cumulative exposure.