Type of chlorinated solvent | Exposure risk value >0 a | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Controls | Any type of limb deficiency | Adjusted odds ratiob(95% CI) | Longitudinal limb deficiency | Adjusted odds ratiob(95% CI) | Transverse limb deficiency | Adjusted odds ratiob(95% CI) | ||||||||
n | % | n | % | n | % | n | % | |||||||
Any type | 63599 | 26.2 | 568 | 28.7 | 1.05 | (0.94, 1.17) | 252 | 29.3 | 0.97 | (0.82, 1.14) | 334 | 27.7 | 1.09 | (0.94, 1.26) |
Carbon tetrachloride | 4568 | 1.9 | 39 | 2.0 | 1.07 | (0.77, 1.49) | 17 | 2.0 | 0.97 | (0.59, 1.61) | 21 | 1.7 | 1.01 | (0.64, 1.58) |
Chloroform | 3985 | 1.6 | 37 | 1.9 | 1.11 | (0.79, 1.57) | 16 | 1.9 | 1.04 | (0.62, 1.74) | 20 | 1.7 | 1.03 | (0.65, 1.63) |
1,1-dichloroethane | 1847 | 0.8 | 14 | 0.7 | 1.00 | (0.59, 1.71) | 7 | 0.8 | 1.09 | (0.51, 2.32) | 7 | 0.6 | 0.87 | (0.41, 1.85) |
1,2-dichloroethane | 6637 | 2.7 | 52 | 2.6 | 0.98 | (0.73, 1.32) | 24 | 2.8 | 0.95 | (0.62, 1.46) | 29 | 2.4 | 0.96 | (0.65, 1.42) |
1,2-dichloroethylene | 2026 | 0.8 | 17 | 0.9 | 1.09 | (0.67, 1.78) | 8 | 0.9 | 1.11 | (0.54, 2.26) | 8 | 0.7 | 0.89 | (0.44, 1.80) |
Ethyl chloride | 5271 | 2.2 | 43 | 2.2 | 1.00 | (0.73, 1.37) | 20 | 2.3 | 1.01 | (0.64, 1.61) | 23 | 1.9 | 0.92 | (0.60, 1.41) |
Methyl chloroform | 5294 | 2.2 | 46 | 2.3 | 0.94 | (0.69, 1.27) | 23 | 2.7 | 0.97 | (0.63, 1.48) | 23 | 1.9 | 0.82 | (0.54, 1.26) |
Methylene chloride | 38448 | 15.9 | 361 | 18.2 | 1.06 | (0.94, 1.20) | 164 | 19.1 | 1.01 | (0.84, 1.22) | 204 | 16.9 | 1.04 | (0.88, 1.23) |
Perchloroethylene | 29854 | 12.3 | 272 | 13.7 | 1.10 | (0.96, 1.26) | 113 | 13.2 | 0.95 | (0.77, 1.17) | 167 | 13.9 | 1.21 | (1.01, 1.45) |
Propylene dichloride | 1518 | 0.6 | 13 | 0.7 | 1.15 | (0.66, 2.00) | 6 | 0.7 | 1.13 | (0.50, 2.56) | 6 | 0.5 | 0.93 | (0.41, 2.09) |
Tetrachloroethane | 1955 | 0.8 | 14 | 0.7 | 0.99 | (0.58, 1.69) | 6 | 0.7 | 0.93 | (0.41, 2.10) | 7 | 0.6 | 0.86 | (0.40, 1.83) |
1,1,2-trichloroethane | 2561 | 1.1 | 18 | 0.9 | 0.91 | (0.56, 1.46) | 8 | 0.9 | 0.86 | (0.42, 1.75) | 9 | 0.7 | 0.79 | (0.40, 1.54) |
Trichloroethylene | 28547 | 11.8 | 257 | 13.0 | 1.01 | (0.88, 1.17) | 119 | 13.9 | 1.00 | (0.81, 1.24) | 149 | 12.4 | 1.04 | (0.86, 1.26) |
1,2,3-trichloropropane | 2847 | 1.2 | 24 | 1.2 | 1.10 | (0.72, 1.67) | 11 | 1.3 | 1.08 | (0.58, 1.99) | 12 | 1.0 | 0.95 | (0.53, 1.71) |