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Table 2 Summary of near-highway health effects studies

From: Near-highway pollutants in motor vehicle exhaust: A review of epidemiologic evidence of cardiac and pulmonary health risks

Citation

Location

Highway traffic intensitya

Pollutants measuredb

Distance from highway

Health Outcomes

Statistical associatione

Schwartz et al. 2005 (22)

Boston

NA

PM2.5, BC, CO

NA

Heart rate variability

Decreases in measures of heart rate variability

Adar et al. 2007 (23)

St. Louis, Missouri

NA

PM2.5, BC, UFP

On highway in busses

Heart rate variability

Decreases in measures of heart rate variability

Hoek et al. 2002 (24)

Netherlands

NA

BC, NO2

Continuous d

Cardio-pulmonary mortality, lung cancer

1.41 OR for living near road

Tonne et al. 2007 (41)

Worchester, Mass.

NA

PM2.5

Continuous d

Acute myocardial infarction (AMI)

5% increase in odds of AMI

Venn et al. 2001 (49)

Nottingham, UK

NA

NA

Continuous d

Wheezing in children

1.08 OR for living w/in 150 m of road

Nicolai et al. 2003 (58)

Munich, Germany

>30,000 veh/d

Soot, benzene, NO2

Traffic counts within 50 m of house

Asthma, respiratory symptoms, allergy

1.79 OR for asthma and high traffic volume

Gauderman et al. 2005 (65)

Southern California

 

NO2

Continuous d

Asthma, respiratory symptoms

Increased asthma closer to freeways

McConnell et al. 2006 (57)

Southern California

NA

NA

Continuous d

Asthma

Large risk for children living w/in 75 m of road

Ryan, et al. 2007 (59)

Cincinnati, Ohio

> 1,000 trucks/d

PM2.5

400 m

Wheezing in children

NA

Kim et al. 2004 (60)

San Francisco

90,000 – 210,000 veh/d

PM, BC, NOx

School sites

Childhood asthma

1.07 OR for high levels of NOx

Wjst et al. 1993 (68)

Munich, Germany

7,000–125,000 veh/d

NOx, CO

School sites

Asthma, bronchitis

Several statistical associations found

Brunekreef et al. 1997 (69)

Netherlands

80,000 – 152,000 veh/d

PM10, NO2

Continuousd

Lung function

Decreased FEV with proximity to high truck traffic

Janssen et al. 2003 (74)

Netherlands

30,000–155,000 veh/d

PM2.5, NO2, benzene

< 400 m c

Lung function, respiratory symptoms

No association with lung function

Peters et al. 1999 (82)

Southern California

NA

PM10, NO2

NA

Asthma, bronchitis, cough, wheeze

1.54 OR of wheeze for boys with exposure to NO2

Brauer et al. 2007 (67)

Netherlands

Highways and streets

PM2.5, NO2, soot

Modeled exposure

Asthma, allergy, bronchitis, respiratory symptoms

Strongest association was with food allergies

Visser et al. 2004 (91)

Amsterdam

> 10,000 veh/d

NA

NA

Cancer

Multiple associations

Vineis et al. 2006 (87)

10 Eurpoean countries

NA

PM10, NO2, SO2

NA

Cancer

1.46 OR near heavy traffic, 1.30 OR for high exposure to NO2

Gauderman et al. 2007 (73)

Southern California

NA

PM10, NO2

Continuousd

Lung Function

Decreased FEV for those living near freeway

  1. aAs defined in article cited (veh/d = vehicles per day; veh/h = vehicles per hour).
  2. bUFP = ultrafine particles; FP = fine particles; PM2.5 = particles with aerodynamic diameter ≤ 2.5 um; PM10 = particles with aerodynamic diameter ≤ 10 um; BC = black carbon; PPAH = particle-bound polycyclic aromatic hydrocarbons; VOCs = volatile organic compounds
  3. cPollutant measurements were made along a transect away from the highway
  4. dProximity of each participant to a major road was calculated using GIS software
  5. eStatistical association between proximity to highway or exposure to traffic-generated pollutants and measured health outcomes
  6. NA = not applicable; measurements were not made.