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Table 4 Odds ratios (OR) for a male birth among offspring from parents in the Michigan Long-Term PBB Study with enrollment serum PCB concentrations

From: A cohort study of the association between secondary sex ratio and parental exposure to polybrominated biphenyl (PBB) and polychlorinated biphenyl (PCB)

  

N (%)

Crude^

Unadjusted *

Adjusted**

Exposure Variables (μg/L)

 

Offspring

OR (95% CI)

OR (95% CI)

OR (95% CI)

Model 1 (Maternal PCB only):

    

   Maternal PCB

 

790

   

   < 6

 

444 (56)

1.00

1.00

1.00

   ≥ 6

 

346 (44)

1.02 (0.77, 1.35)

0.99 (0.76, 1.30)

1.01 (0.77, 1.32)

Model 2 (Paternal PCB only):

    

   Paternal PCB

 

253

   

   < 8

 

141 (56)

1.00

1.00

1.00

   ≥ 8

 

112 (44)

1.06 (0.64, 1.75)

1.23 (0.83, 1.82)

1.24 (0.81, 1.88)

Model 3 (Maternal and Paternal PCB combined):

  

Maternal PCB

Paternal PCB

253

   

< 6

< 8

80 (32)

1.00

1.00

1.00

other combinations

116 (46)

1.26 (0.71, 2.22)

1.23 (0.77, 1.97)

1.00 (0.63, 1.57)

≥ 6

≥ 8

57 (22)

1.13 (0.57, 2.24)

1.39 (0.81, 2.40)

1.53 (0.93, 2.52)

  1. ^ Crude ORs are unadjusted for covariates or offspring born to the same mother or father
  2. * ORs are unadjusted for covariates, but adjusted for offspring born to the same mother or father
  3. ** AORs are adjusted for covariates (Model 1 adjusted for year of offspring's birth; Models 2 and 3 adjusted for year of offspring's birth and paternal BMI as low and normal vs. high) and adjusted for offspring born to the same mother or father