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Table 4 Results of cancer incidence analyses in the Seveso population*, 1977-96, by time since the accident.

From: Cancer incidence in the population exposed to dioxin after the "Seveso accident": twenty years of follow-up

Cancer sites

Zone

 

Years since the accident

   

0-4

5-9

10-14

15 +

All cancers

A

N

8

8

9

19

  

RR

1.06

0.84

0.83

1.27

  

95% CI

0.53-2.12

0.42-1.68

0.43-1.60

0.81-2.00

 

B

N

55

51

72

92

  

RR

1.13

0.84

1.05

1.02

  

95% CI

0.87-1.48

0.63-1.10

0.83-1.32

0.83-1.26

 

R

N

339

411

455

603

  

RR

0.94

0.93

0.96

0.99

  

95% CI

0.84-1.06

0.84-1.03

0.87-1.06

0.90-1.07

Lung cancer

A

N

1

1

1

4

  

RR

0.84

0.73

0.57

2.04

  

95% CI

0.12-5.96

0.10-5.19

0.08-4.08

0.76-5.47

 

B

N

8

8

9

12

  

RR

1.02

0.89

0.86

1.09

  

95% CI

0.50-2.05

0.44-1.79

0.44-1.66

0.61-1.93

 

R

N

37

70

83

90

  

RR

0.66

1.09

1.15

1.20

  

95% CI

0.47-0.92

0.84-1.41

0.91-1.46

0.95-1.50

Lymphatic and hematopoietic tissue cancer

A

N

-

-

1

3

  

RR

  

1.39

2.96

  

95% CI

  

0.20-9.96

0.95-9.22

 

B

N

9

5

9

6

  

RR

2.39

1.33

1.92

0.95

  

95% CI

1.22-4.69

0.55-3.25

0.98-3.75

0.42-2.12

 

R

N

20

27

32

42

  

RR

0.75

1.03

1.01

1.00

  

95% CI

0.47-1.20

0.68-1.55

0.70-1.48

0.72-1.38

Non-Hodgkin's lymphoma

A

N

-

-

-

1

  

RR

   

1.97

  

95% CI

   

0.27-14.07

 

B

N

2

2

5

3

  

RR

1.75

1.37

2.30

0.94

  

95% CI

0.43-7.20

0.34-5.62

0.93-5.66

0.30-2.96

 

R

N

5

15

8

21

  

RR

0.61

1.44

0.54

0.99

  

95% CI

0.24-1.53

0.82-2.53

0.26-1.12

0.62-1.58

Leukemia

A

N

-

-

1

1

  

RR

  

5.11

3.26

  

95% CI

  

0.71-37.07

0.45-23.44

 

B

N

3

1

2

2

  

RR

1.90

0.85

1.55

1.05

  

95% CI

0.60-6.05

0.12-6.15

0.38-6.37

0.26-4.29

 

R

N

6

8

14

3

  

RR

0.55

0.98

1.60

0.24

  

95% CI

0.24-1.26

0.46-2.07

0.88-2.90

0.07-0.75

Multiple myeloma

A

N

-

-

-

1

  

RR

   

8.35

  

95% CI

   

1.14-61.31

 

B

N

2

2

2

-

  

RR

3.56

4.76

4.47

 
  

95% CI

0.85-15.00

1.11-20.38

1.04-19.20

 
 

R

N

1

2

4

11

  

RR

0.23

0.63

1.28

2.24

  

95% CI

0.03-1.70

0.15-2.68

0.44-3.77

1.11-4.49

Breast cancer (females only)

A

N

-

1

2

5

  

RR

 

0.81

1.42

2.57

  

95% CI

 

0.11-5.74

0.35-5.68

1.07-6.20

 

B

N

4

6

10

10

  

RR

0.70

0.79

1.09

0.78

  

95% CI

0.26-1.87

0.35-1.76

0.58-2.04

0.42-1.46

 

R

N

48

59

55

87

  

RR

1.10

1.07

0.87

1.01

  

95% CI

0.81-1.49

0.81-1.41

0.66-1.15

0.81-1.27

  1. *Subjects aged < 75 years, resident in the area at the accident time.
  2. ICD-9: International Classification of Diseases, Ninth Revision; N: number of cases; RR: rate ratios calculated with Poisson regression, adjusted for gender and age category; 95% CI: 95% confidence interval.
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