Skip to main content

Table 3 Crude and adjusted ORs for male breast cancer by exposure status

From: Evaluation of contaminated drinking water and male breast cancer at Marine Corps Base Camp Lejeune, North Carolina: a case control study

Exposure

Controls

Cases

OR (95 % CI)

p-value

aORa (95 % CI)

p-value

# (%)

# (%)

Ever stationed at Camp Lejeune

No

248 (66.5)

41 (57.7)

1.00 (ref.)

 

1.00 (ref.)

 

Yes

125 (33.5)

30 (42.3)

1.45 (0.86-2.44)

0.16

1.14 (0.65-1.97)

0.65

Cumulative PCE

No exposure

357 (96.0)

67 (94.4)

1.00 (ref.)

 

1.00 (ref.)

 

Low (>0- < 36 ppb-months)

7 (1.9)

2 (2.8)

1.52 (0.21-7.00)

0.59

1.05 (0.14-5.14)

0.91

High (≥36 ppb-months)

8 (2.2)

2 (2.8)

1.33 (0.19-5.91)

0.69

1.20 (0.16-5.89)

0.80

Cumulative TCE

No exposure

258 (69.4)

46 (64.8)

1.00 (ref.)

 

1.00 (ref.)

 

Low (>0- <159 ppb-months)

57 (15.3)

13 (18.3)

1.28 (0.63-2.49)

0.48

1.06 (0.50-2.13)

0.86

High (≥159 ppb-months)

57 (15.3)

12 (16.9)

1.18 (0.57-2.34)

0.63

0.93 (0.43-1.90)

0.85

Cumulative benzene

No exposure

260 (69.9)

46 (64.8)

1.00 (ref.)

 

1.00 (ref.)

 

Low (>0- < 3.6 ppb-months)

57 (15.3)

15 (21.1)

1.49 (0.76-2.82)

0.24

1.67 (0.82-3.30)

0.15

High (≥3.6 ppb-months)

55 (14.8)

10 (14.1)

1.03 (0.47-2.18)

0.92

0.57 (0.24-1.25)

0.17

Cumulative DCE

No exposure

356 (95.7)

67 (94.4)

1.00 (ref.)

 

1.00 (ref.)

 

Low (>0- <472 ppb-months)

8 (2.2)

1 (1.4)

0.67 (0.03-4.25)

0.78

0.56 (0.02-3.83)

0.67

High (≥472 ppb-months)

8 (2.2)

3 (4.2)

1.99 (0.42-7.47)

0.34

1.50 (0.30-6.11)

0.57

Cumulative vinyl chloride

No exposure

356 (95.7)

67 (94.4)

1.00 (ref.)

 

1.00 (ref.)

 

Low (>0- <60 ppb-months)

8 (2.2)

2 (2.8)

1.33 (0.19-5.89)

0.69

0.94 (0.13-4.38)

0.99

High (≥60 ppb-months)

8 (2.2)

2 (2.8)

1.33 (0.19-5.89)

0.69

1.19 (0.16-5.89)

0.81

Cumulative TVOCb

No exposure

258 (84.9)

46 (64.8)

1.00 (ref.)

 

1.00 (ref.)

 

Low (>0- <168 ppb-months)

57 (15.3)

14 (19.7)

1.38 (0.69-2.64)

0.35

1.18 (0.57-2.33)

0.64

High (≥168 ppb-months)

57 (15.3)

11 (15.5)

1.08 (0.51-2.18)

0.81

0.82 (0.37-1.72)

0.63

Monthly average PCE

No exposure

357 (96.0)

67 (94.4)

1.00 (ref.)

 

1.00 (ref.)

 

Low (>0- < 2 ppb)

8 (2.2)

2 (2.8)

1.33 (0.19-5.90)

0.69

0.91 (0.13-4.21)

0.96

High (≥2 ppb)

7 (1.9)

2 (2.8)

1.52 (0.21-7.00)

0.59

1.47 (0.18-7.91)

0.65

Monthly average TCE

No exposure

258 (69.4)

46 (64.8)

1.00 (ref.)

 

1.00 (ref.)

 

Low (>0- <17.5 ppb)

57 (15.3)

8 (11.3)

0.79 (0.33-1.71)

0.58

1.02 (0.42-2.30)

0.93

High (≥17.5 ppb)

57 (15.3)

17 (23.9)

1.67 (0.88-3.10)

0.12

0.97 (0.47-1.94)

0.94

Monthly average benzene

No exposure

260 (69.9)

46 (64.8)

1.00 (ref.)

 

1.00 (ref.)

 

Low (>0- < 0.4 ppb)

56 (15.1)

9 (12.7)

0.91 (0.40-1.92)

0.83

1.23 (0.52-2.72)

0.61

High (≥0.4 ppb)

56 (15.1)

16 (22.5)

1.61 (0.83-3.03)

0.15

0.87 (0.42-1.78)

0.72

Monthly average DCE

No exposure

356 (95.7)

67 (94.4)

1.00 (ref.)

 

1.00 (ref.)

 

Low (>0- < 94 ppb)

8 (2.2)

2 (2.8)

1.33 (0.20-5.90)

0.69

0.88 (0.12-4.01)

0.92

High (≥94 ppb)

8 (2.2)

2 (2.8)

1.33 (0.20-5.90)

0.69

1.32 (0.17-6.77)

0.73

Monthly average vinyl chloride

No exposure

356 (95.7)

67 (94.4)

1.00 (ref.)

 

1.00 (ref.)

 

Low (>0- <3.4 ppb)

8 (2.2)

2 (2.8)

1.33 (0.20-5.90)

0.69

0.94 (0.13-4.37)

0.99

High (≥3.4 ppb)

8 (2.2)

2 (2.8)

1.33 (0.20-5.90)

0.69

1.19 (0.16-5.89)

0.81

Monthly average TVOCb

No exposure

258 (69.4)

46 (64.8)

1.00 (ref.)

 

1.00 (ref.)

 

Low (>0- <18 ppb)

58 (15.6)

9 (12.7)

0.87 (0.38-1.83)

0.75

1.15 (0.49-2.51)

0.72

High (≥18 ppb)

56 (15.1)

16 (22.5)

1.60 (0.83-3.01)

0.16

0.89 (0.43-1.80)

0.76

  1. aadjusted for age at diagnosis, race, and service in Vietnam; bsum of the amount of exposure to PCE, TCE, benzene, DCE, and vinyl chloride