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Table 2 Fully-adjusted, survey-weighted associations between serum PBDE concentrations and having a current thyroid problem. Adjusted for: age, race/ethnicity, BMI, education, smoking, alcohol consumption, and current hormone use

From: PBDE flame retardants, thyroid disease, and menopausal status in U.S. women

 

BDE47 n = 1075

BDE99 n = 1061

BDE100 n = 1089

BDE153 n = 1089

Sum BDEs n = 1061

 

OR

(95 % CI)

OR

(95 % CI)

OR

(95 % CI)

OR

(95 % CI)

OR

(95 % CI)

Men and Women Combined

Q1 + Q2 (ref)

1

 

1

 

1

 

1

 

1

 

Q3

0.55

(0.20–1.49)

0.93

(0.38–2.27)

0.74

(0.44–1.25)

0.92

(0.30–2.84)

0.57

(0.23–1.39)

Q4

1.32

(0.90–1.96)

1.22

(0.80–1.84)

1.13

(0.79–1.60)

1.14

(0.56–2.31)

1.09

(0.71–1.67)

 

BDE47 n = 512

BDE99 n = 504

BDE100 n = 518

BDE153 n = 518

Sum BDEs n = 504

All Women

Q1 + Q2 (ref)

1

 

1

 

1

 

1

 

1

 

Q3

0.60

(0.19–1.85)

0.75

(0.27–2.08)

0.65

(0.27–1.54)

1.00

(0.27–3.78)

0.36**

(0.15–0.89)

Q4

1.48**

(1.05–2.09)

1.78**

(1.16–2.75)

1.50*

(0.97–2.31)

1.44

(0.68–3.05)

1.61**

(1.10–2.36)

 

BDE47 n = 236

BDE99 n = 233

BDE100 n = 240

BDE153 n = 240

Sum BDEs n = 233

Postmenopausal Women

Q1 + Q2 (ref)

1

 

1

 

1

 

1

 

1

 

Q3

0.81

(0.24–2.71)

0.99

(0.34–2.93)

0.23**

(0.07–0.68)

0.50

(0.13–1.90)

0.54

(0.15–1.97)

Q4

2.15*

(0.86–5.37)

3.63**

(1.12–11.8)

2.02*

(0.93–4.36)

1.25

(0.49–3.21)

2.20*

(0.92–5.26)

  1. ***p < 0.01,**p < 0.05, *p < 0.1