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Table 5 Association between the replicated SNPs and blood lead levels according to alcohol consumption status

From: Exome-wide association study identifies genetic polymorphisms of C12orf51, MYL2, and ALDH2 associated with blood lead levels in the general Korean population

SNP ID

Gene symbol

Non-drinkers (N = 361)

Drinkers (N = 1120)

 

βa

SE

P-value

βa

SE

P-value

P for interaction

rs41268474

C1orf68

0.278

0.111

0.012

0.024

0.072

0.741

0.099

rs11066280

C12orf51

−0.068

0.062

0.275

−0.137

0.053

0.010

0.191

rs12229654

MYL2

−0.073

0.068

0.284

−0.157

0.058

0.007

0.369

rs671

ALDH2

−0.069

0.062

0.266

−0.182

0.057

0.002

0.067

  1. SNPs were coded using an additive genetic model
  2. aAdjusted for age, sex, smoking status and dietary lead intake