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Table 6 Association between the replicated SNPs and blood lead levels according to dietary calcium intake

From: Exome-wide association study identifies genetic polymorphisms of C12orf51, MYL2, and ALDH2 associated with blood lead levels in the general Korean population

SNP ID

Gene symbol

Dietary calcium intake, mg/day

P for interaction

Low (<473) (N = 494)

Medium (473–760) (N = 493)

High (>760) (N = 494)

βa

SE

P-value

βa

SE

P-value

βa

SE

P-value

rs41268474

C1orf68

0.046

0.111

0.679

0.131

0.098

0.181

0.078

0.111

0.484

0.776

rs11066280

C12orf51

−0.147

0.073

0.043

−0.126

0.072

0.081

−0.066

0.069

0.335

0.661

rs12229654

MYL2

−0.154

0.077

0.047

−0.141

0.082

0.084

−0.089

0.078

0.253

0.821

rs671

ALDH2

−0.165

0.077

0.033

−0.155

0.074

0.037

−0.094

0.072

0.190

0.797

  1. SNPs were coded using an additive genetic model
  2. aAdjusted for age, sex, smoking status, drink and dietary lead intake