Table 5 Standardized path coefficients depicting the relationship between 5 chemicals, cognitive functioning and covariates for females and males age years old, NHANES 1999-2002
Path | Path coefficient (95% CI) p-value | |||
|---|---|---|---|---|
Lipid-adjusted | Non-lipid-adjusted | Lipid-adjusted | Non-lipid-adjusted | |
Males (N = 231) | ||||
PCB 74 → DSC | 0.03 (−0.11, 0.17) | 0.03 (−0.13, 0.18) | 0.66 | 0.74 |
PCB 118 → DSC | −0.01 (−0.25, 0.22) | −0.002 (−0.26, 0.26) | 0.92 | 0.99 |
PCB 146 → DSC | −0.09 (−0.31, 0.13) | −0.11 (−0.36, 0.14) | 0.42 | 0.38 |
PCB 153 → DSC | 0.05 (−0.22, 0.32) | 0.05 (−0.25, 0.35) | 0.72 | 0.74 |
Lead → DSC | −0.09 (−0.24, 0.06) | −0.09 (−0.23, 0.06) | 0.23 | 0.23 |
aPIR2 → DSC | 0.21 (0.05, 0.36) | 0.21 (0.06, 0.36) | 0.01 | 0.008 |
bPIR3 → DSC | 0.39 (0.21, 0.58) | 0.39 (0.21, 0.58) | <0.001 | <0.001 |
cED2 → DSC | 0.20 (0.10, 0.30) | 0.20 (0.11, 0.30) | <0.001 | <0.001 |
dED3 → DSC | 0.25 (0.15, 0.36) | 0.25 (0.14, 0.36) | <0.001 | <0.001 |
eED4 → DSC | 0.35 (0.20, 0.50) | 0.35 (0.20, 0.50) | <0.001 | <0.001 |
fMA → DSC | −0.10 (−0.16, −0.03) | −0.10 (−0.16, −0.03) | 0.003 | 0.002 |
gOH → DSC | −0.17 (−0.35, 0.02) | −0.17 (−0.36, 0.02) | 0.09 | 0.08 |
hNHB → DSC | −0.14 (−0.23, −0.05) | −0.14 (−0.23, −0.05) | 0.003 | 0.002 |
Age → DSC | −0.27 (−0.36, −0.18) | −0.27 (−0.36, −0.18) | <0.001 | <0.001 |
Smoke → DSC | 0.05 (−0.10, 0.20) | 0.05 (−0.10, 0.21) | 0.51 | 0.51 |
Females (N = 267) | ||||
PCB 74 → DSC | 0.005 (−0.25, 0.26) | 0.008 (−0.24, 0.26) | 0.97 | 0.95 |
PCB 118 → DSC | −0.12 (−0.32, 0.08) | −0.12 (−0.33, 0.08) | 0.25 | 0.24 |
PCB 146 → DSC | −0.21 (−0.45, 0.03) | −0.22 (−0.46, 0.03) | 0.08 | 0.08 |
PCB 153 → DSC | 0.32 (0.05, 0.59) | 0.33 (0.05, 0.61) | 0.02 | 0.02 |
Lead → DSC | −0.12 (−0.26, 0.01) | −0.12 (−0.26, 0.01) | 0.08 | 0.05 |
PIR2 → DSC | 0.15 (0.000, 0.31) | 0.16 (0.002, 0.31) | 0.05 | <0.001 |
PIR3 → DSC | 0.19 (0.03, 0.34) | 0.19 (0.03, 0.34) | 0.02 | 0.0001 |
ED2 → DSC | 0.28 (0.15, 0.41) | 0.28 (0.15, 0.41) | <0.001 | <0.0001 |
ED3 → DSC | 0.23 (0.09, 0.36) | 0.23 (0.09, 0.36) | 0.001 | <0.001 |
ED4 → DSC | 0.22 (0.11, 0.33) | 0.22 (0.11, 0.33) | <0.001 | 0.02 |
MA → DSC | −0.13 (−0.19, −0.06) | −0.13 (−0.19, −0.06) | <0.001 | <0.001 |
OH → DSC | −0.15 (−0.27, −0.03) | −0.15 (−0.27, −0.03) | 0.02 | 0.11 |
NHB → DSC | −0.19 (−0.27, −0.11) | −0.19 (−0.27, −0.11) | <0.001 | <0.001 |
Age → DSC | −0.37 (−0.48, −0.25) | −0.37 (−0.49, −0.25) | <0.001 | <0.001 |
Smoke → DSC | −0.08 (−0.22, 0.06) | −0.08 (−0.22, 0.06) | 0.28 | 0.28 |