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Table 3 Urinary OP concentrations (creatinine adjusted and unadjusted and molar) in pregnant women from INMA-Valencia cohort (Spain, 2003–2006, n = 573)

From: Distributions and determinants of urinary biomarkers of organophosphate pesticide exposure in a prospective Spanish birth cohort study

   

Creatinine adjusted (μg/g)

Unadjusted (μg/L)

Molar concentrations creatinine adjusted (nm/g)

Molar concentrations (nm/L)

 

N > LOD

% > LOD

Min

Max

GM

95% CI

Min

Max

GM

95% CI

GM

95% CI

GM

95% CI

DEP

50

8.7

<LOD

66.4

1.04

0.54

2.00

<LOD

71.2

1.73

1.05

2.85

6.66

3.55

12.47

11.23

6.81

18.52

DETP

43

7.5

<LOD

56.5

0.09

0.03

0.27

<LOD

32.0

0.22

0.1

0.49

0.60

0.21

1.68

1.29

0.57

2.91

DMTP

308

53.8

<LOD

1023.0

2.76

2.23

3.42

<LOD

940.4

2.39

1.93

2.97

19.45

15.69

24.11

16.83

13.56

20.89

DMDTP

88

15.4

<LOD

189.5

0.06

0.03

0.14

<LOD

467.2

0.07

0.03

0.14

0.50

0.24

1.07

0.42

0.19

0.91

DEAMPY

32

5.6

<LOD

394.3

0.02

0.01

0.09

<LOD

293.0

0.03

0.01

0.12

0.14

0.04

0.56

0.19

0.05

0.67

IMPY

67

11.7

<LOD

787.5

0.02

0.01

0.07

<LOD

744.2

0.03

0.01

0.07

0.19

0.07

0.54

0.17

0.06

0.48

PNP

56

9.8

<LOD

28.7

0.04

0.02

0.09

<LOD

24.0

0.04

0.02

0.09

0.33

0.15

0.73

0.29

0.12

0.66

TCPY

224

39.1

<LOD

142.3

0.57

0.45

0.72

<LOD

117.3

0.49

0.39

0.62

2.88

2.29

3.62

2.47

1.95

3.13

sumDEP

76

13.3

6.6

98.2

3.07

2.21

4.27

6.6

78.0

4.72

3.76

5.93

19.57

14.11

27.13

29.78

23.71

37.42

sumDMP

314

54.8

1.6

1023.8

4.84

4.05

5.77

1.6

1015.8

4.2

3.52

5.02

32.79

27.44

39.19

28.48

23.81

34.07

sumDAP

337

58.8

8.2

1030.4

16.29

14.67

18.09

8.2

1022.4

14.64

13.25

16.18

107.25

96.45

119.27

96.15

86.87

106.42

sumOP

283

49.4

2.4

789.1

3.83

3.36

4.36

2.4

745.8

3.44

3.03

3.91

22.41

19.69

25.51

20.18

17.78

22.91

  1. The detection frequency for the summed variables was defined as the proportion of individuals with at least one detected compound
  2. DEP Diethyl phosphate; DETP Diethyl thiophosphate; DMTP Dimethyl thiophosphate; DMDTP Dimethyl dithiophosphate; DEAMPY 2-diethylamino-6-methyl-4-pyrimidinol; IMPY 2-isopropyl-4-methyl-6-hydroxypyrimidine; PNP para-nitrophenol; TCPY 3,5,6-trichloro-2-pyridinol; sumDEP DEP + DETP; sumDMP DMTP + DMDTP; sumDAP sumDEP + sumDMP; sumOP DEAMPY + IMPY + PNP + TCPy
  3. The limit of determination was 10 μg/L for DEP, 2.3 μg/L for DETP, 1.6 μg/L for DMTP, 1.6 μg/L for DMDTP, 0.8 μg/L for TCPY, 0.8 μg/L for PNP, 1.6 μg/L for DEAMPY, and 1.6 μg/L for IMPY.
  4. LOD limit of determination
  5. Min minimum value
  6. Max maximum value
  7. GM geometric mean