Table 3 Model estimates for the association between maternal total urinary BPA (log10 ng/mL) concentration and infant salivary cortisol concentration (natural log μg/dL): n = 132
Model 1: BPA | Model 2: BPA with sex | Model 3: BPA with sex and creatinine | ||||
|---|---|---|---|---|---|---|
Fixed Effects | β Coefficient (95% CI) | % change (95% CI) | β Coefficient (95% CI) | % change (95% CI) | β Coefficient (95% CI) | % change (95% CI) |
INTERCEPT (baseline cortisol) | .31 (.12, .49) | GM = .37 μg/dL at baseline | .31 (.12, .50) | GM = .38 μg/dL at baseline for females | .31 (.12, .50) | GM = .38 μg/dL at baseline for females |
Time of day for urine collection (hours) | .001 (−.006, .008) | .002 (−.005, .009) | .002 (−.005, .009) | |||
Gestational age at urine collection (weeks) | −.004 (−.01, .003) | −.005 (−.01, .003) | −.005 (−.01, .003) | |||
Gestational age at birth (weeks) | −.005 (−.02, .01) | −.006 (−.02, .01) | −.005 (−.02, .01) | |||
Creatinine (mmol/L) | .0001 (−.005, .005) | |||||
Infant Sex | −.02 (−.07, .03) | −.02 (−.07, .03) | ||||
BPA (log10 ng/mL) | .002 (−.08, .08) | .2% (−.8, .8) increase per 10-fold increase in BPA at baseline | .13 (.01, .26) | 14% (.7, 30) increase per 10-fold increase in BPA at baseline for females | .13 (−.01, .28) | 14% (−1, 32) increase per 10-fold increase in BPA at baseline for females |
BPA X sex | −.22 (−.39, −.05) | −20% (−32, −5) difference between males and females; net effect is 8.1% decrease per 10-fold increase in BPA at baseline for males | −.22 (−.39, −.05) | −20% (−32, −5) difference between males and females; net effect is a 9% decrease per 10-fold increase in BPA at baseline for males | ||
TIME 2 (hours) | −.33 (−.47, −.18) | −.33 (−.48, −.18) | −.33 (−.48, −.18) | |||
TIME (hours) | .31 (.19, .44) | 37% (21, 55) increase per hour | .32 (.19, .46) | 38% (21, 58) increase per hour for females | .32 (.19, .45) | 38% (21, 57) per hour for females |
Gestational age at birth (weeks) | −.02 (−.04, .01) | −.02 (−.04, .01) | −.02 (−.04, .01) | |||
Creatinine (mmol/L) | .003 (−.005, .01) | |||||
Infant Sex | −.03 (−.11, .05) | −3% (−10, 5) difference between males and females; net effect is 34% increase per hour in males | −.02 (−.11, .06) | −3% (−10, 5) difference between males and females; net effect is 34% increase per hour in males | ||
BPA (log10 ng/mL) | .02 (−.11, .15) | 2% (−10, 17) per hour per 10-fold increase in BPA | −.15 (−.35, .05) | −14% (−30, 5) decrease per hour for females per 10-fold increase in BPA | −.20 (−.43, .03) | −18% (−35, 3) decrease per hour for females per 10-fold increase in BPA |
BPA X sex | .30 (.04, .56) | 35% (4, 75) difference between males and females; net effect is a 17% per hour increase in males per 10-fold increase in BPA | .33 (.06, .60) | 39% (6, 82) difference between males and females; net effect is a 15% per hour increase in males per 10-fold increase in BPA | ||