Sex | Cluster label | Source: pathway | # genes | Direction of regulation |
---|---|---|---|---|
Girls | Aurora B pathway | PID: Aurora B pathway | 36 | DOWN |
Core matrisome | Matrisome: Naba core matrisome | 142 | DOWN | |
Defensins | Reactome: defensins | 18 | DOWN | |
Extracellular matrix organization | Â | Â | DOWN | |
 | Reactome: extracellular matrix organization | 49 | ||
 | Reactome: degradation of the extracellular matrix | 18 | ||
FOXM1 pathway | PID: FOXM1 pathway | 32 | DOWN | |
Histone related pathways | Â | Â | DOWN | |
 | Reactome: amyloids | 69 | DOWN | |
 | Reactome: RNA polymerase I promotor opening | 54 | DOWN | |
 | KEGG: systemic lupus erythematosus | 116 | DOWN | |
Olfactory signaling | Â | Â | DOWN | |
 | KEGG: olfactory transduction | 124 | DOWN | |
 | Reactome: olfactory signaling pathway | 95 | DOWN | |
Porphyrin metabolism | KEGG: porphyrin and chlorophyll metabolism | 25 | DOWN | |
Ribosome related pathways | Â | Â | UP | |
 | Reactome: peptide chain elongation | 83 | ||
 | KEGG: ribosome | 85 | ||
 | Reactome: nonsense mediated decay enhanced by the exon junction complex | 104 | ||
Transcription-SMAD2,3,4-TGFβ pathways |  |  | UP | |
 | Reactome: generic transcription pathway | 267 | ||
 | Reactome: downregulation of SMAD2, 3, SMAD4 transcriptional activity | 18 | ||
 | Reactome: signaling by TGF-beta receptor complex | 54 | ||
Boys | Apoptotic execution | Reactome: apoptotic execution phase | 43 | UP |
Cell cycle | Â | Â | UP | |
 | Reactome: cell cycle mitotic | 290 | ||
 | Reactome: mitotic prometaphase | 79 | ||
 | Reactome: DNA replication | 176 | ||
HDAC class III | PID: HDAC class III pathway | 22 | UP | |
UPA-UPAR pathway | PID: uPA uPAR pathway | 30 | UP | |
RhoA pathway | PID: RhoA pathway | 37 | UP |