From: Transcriptome-wide analyses indicate mitochondrial responses to particulate air pollution exposure
Characteristics | Discovery cohort (2004–2005) | Validation cohort (2012–2015) | ||
---|---|---|---|---|
Personal | Women (n = 50) | Men (n = 48) | Women (n = 94) | Men (n = 75) |
Age, years | 57.8 [51.2–63.1] | 58.0 [51.5–64.0] | 58.1 [52.6–63.2] | 58.0 [52.5–63.6] |
BMI, kg/m2 | 25.8 [22.1–31.1] | 27.4 [23.0–31.4] | 25.5 [20.4–32.8] | 26.1 [21.6–30.9] |
WBC, cells/mcL |  |  | 6965 [5170–9360] | 6948 [5200–9270] |
Socio-economic status | ||||
 Low | 28 (56.0) | 20 (41.7) | 23 (56.0) | 14 (18.7) |
 Medium | 7 (14.0) | 15 (31.3) | 16 (14.0) | 26 (34.7) |
 High | 15 (30.0) | 13 (27.1) | 55 (30.0) | 35 (46.7) |
Smoking status | ||||
 Non-smokers | 50 (100.0) | 48 (100.0) | 80 (85.1) | 68 (90.7) |
 Smokers | - | - | 14 (14.9) | 7 (9.3) |
Season of blood sampling | ||||
 Cold (October–March) | 40 (80.0) | 40 (83.3) | 40 (42.6) | 27 (36.0) |
 Warm (April–September) | 10 (20.0) | 8 (16.7) | 54 (57.4) | 48 (64.0) |
Time of blood sampling | ||||
  < 12 pm | 44 (88.0) | 41 (85.4) | 7 (7.5) | 0 (0.0) |
 12 pm–3 pm | 6 (12.0) | 7 (14.6) | 25 (26.6) | 20 (26.7) |
 3 pm–6 pm | 0 (0.0) | 0 (0.0) | 43 (45.7) | 32 (42.7) |
  > 8 pm | 0 (0.0) | 0 (0.0) | 19 (20.2) | 23 (30.7) |
Exposure | ||||
 Short-terma PM10, μg/m3 | 29.3 [18.9–41.3] | 30.6 [20.4–41.4] | 19.6 [13.0–26.9] | 17.8 [12.6–24.0] |
 Short-terma PM2.5, μg/m3 | - | - | 12.8 [5.4–26.0] | 11.3 [5.8–17.7] |
 Medium-termb PM10, μg/m3 | 29.7 [24.2–40.5] | 31.5 [25.8–40.6] | 19.7 [13.8–26.7] | 17.5 [13.9–23.8] |
 Medium-termb PM2.5, μg/m3 | - | - | 12.7 [7.4–18.8] | 10.8 [7.6–16.9] |
 Long-termc PM10, μg/m3 | 26.0 [21.4–30.2] | 25.7 [21.4–30.1] | 24.2 [21.3–27.7] | 23.1 [20.8–25.8] |
 Long-termc PM2.5, μg/m3 | 17.8 [15.5–20.5] | 17.6 [15.6–20.3] | 16.0 [14.9–17.5] | 15.5 [14.6–16.5] |
 Week AT, °C | 5.8 [−1.3–11.9] | 3.4 [−1.5–11.6] | 15.4 [12.7–17.3] | 15.2 [12.7–17.3] |
 Month AT, °C | 7.1 [0.6–14.1] | 4.7 [0.6–11.2] | 15.3 [13.2–16.5] | 15.3 [13.2–17.2] |