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Table 1 Participant characteristics by high-sensitivity C-reactive protein (hs-CRP) and plasma homocysteine (tHcy) in women, Buffalo, NY

From: Blood lead, cadmium and mercury in relation to homocysteine and C-reactive protein in women of reproductive age: a panel study

 

Population

(n = 259)

hs-CRP

<0.56 mg/L†

hs-CRP

≥0.56 mg/L†

p-value‡

tHcy

<5.9 μmol/L†

tHcy

≥5.9 μmol/L†

p-value‡

Age, years

27.4 ± 8.2

25.4 ± 7.3

29.5 ± 8.6

<0.01

28.1 ± 8.4

26.9 ± 8.1

0.28

BMI, kg/m2

24.1 ± 3.9

22.5 ± 2.8

25.9 ± 4.1

<0.01

23.9 ± 3.7

24.3 ± 4.0

0.36

Cadmium, μg/La

0.29

(0.26, 0.31)

0.29

(0.26, 0.32)

0.28

(0.25, 0.32)

0.85

0.26

(0.23, 0.30)

0.30

(0.27, 0.34)

0.12

Lead, μg/dLa

0.91

(0.86, 0.96)

0.92

(0.85, 1.00)

0.90

(0.84, 0.98)

0.78

0.83

(0.77, 0.90)

0.97

(0.90, 1.05)

<0.01

Mercury, μg/La

1.05

(0.93, 1.18)

1.03

(0.86, 1.22)

1.07

(0.90, 1.28)

0.72

1.14

(0.94, 1.37)

0.99

(0.84, 1.17)

0.28

Estradiol, pg/mLa, b

51.22

(48.60, 53.98)

50.2

(45.4, 55.5)

50.4

(44.4, 56.7)

0.95

52.6

(46.4, 59.6)

48.9

(44.3, 53.9)

0.35

FSH, mIU/mLa, b

6.59

(6.39, 6.79)

6.51

(6.16, 6.88)

6.50

(6.03, 7.00)

0.97

6.40

(5.92, 6.90)

6.58

(6.21, 6.96)

0.94

LH, ng/mLa, c

9.55

(8.87, 10.30)

9.35

(8.14, 10.74)

9.54

(8.14, 11.18)

0.85

9.39

(8.11, 10.88)

9.48

(8.18, 10.99)

0.93

Progesterone, ng/ml a, d

6.16

(5.60, 6.77)

5.18

(4.18, 6.43)

6.41

(5.33, 7.71)

0.14

6.27

(5.20, 7.56)

5.22

(4.20, 6.49)

0.20

Serum folate, ng/mla

19.89

(19.40, 20.38)

19.8

(18.9, 20.8)

20.0

(19.1, 21.0)

0.70

21.3

(20.2, 22.4)

19.1

(18.3, 19.9)

<0.01

Dietary folate, μg /daya

318.55 (303.0, 334.9)

331.4

(300.5, 365.5)

311.7

(281.0, 345.8)

0.40

349.2

(311.8, 391.2)

305.4

(278.9, 334.4)

<0.01

Dietary Vitamin B6, mg/daya

1.25

(1.19, 1.32)

1.32

(1.19, 1.45)

1.26

(1.13, 1.42)

0.60

1.38

(1.23, 1.54)

1.24

(1.12, 1.37)

0.17

Dietary Vitamin B12, μg /daya

2.53

(2.33, 2.76)

2.67

(2.24, 3.18)

2.64

(2.24, 3.10)

0.92

3.06

(2.16, 3.58)

2.42

(2.05, 2.86)

0.04

Alcohol, litre/daya

0.14

(010, 0.21)

0.13

(0.06, 0.27)

0.20

(0.09, 0.47)

0.43

0.14

(0.05, 0.38)

0.17

(0.09, 0.33)

0.76

Total calories, Kcal/daya

1482.8

(1433, 1534)

1454

(1355, 1560)

1487

(1378, 1605)

0.67

1562

(1432, 1702)

1415

(1328, 1508)

0.06

Racee

       

 White

148 (57)

71 (55)

77 (64)

0.18

56 (56)

92 (61)

0.24

 Black

51 (20)

26 (20)

25 (21)

26 (26)

25 (17)

 Asian

35 (14)

24 (19)

11 (9)

11 (11)

24 (16)

 Other

25 (10)

8 (6)

7 (6)

7 (7)

8 (5)

Smokinge

       

 No/former

249 (96)

125 (97)

114 (95)

0.53

98 (98)

141 (54)

0.30

 Current

10 (4)

4 (3)

6 (5)

2 (2)

8 (5)

Paritye

       

 0

187 (74)

109 (83)

78 (64)

<0.01

66 (65)

121 (80)

<0.01

  ≥ 1

66 (26)

22 (17)

44 (36)

36 (35)

30 (20)

  1. aGeometric mean (95% confidence limits) b Day 7 c Day 14 d Day 22
  2. eCategorical variables [race, smoking, parity] expressed as n (%)
  3. †tHcy and hs-CRP concentrations dichotomized on cycle 1 day 7
  4. ‡Continuous variables compared using t-test; categorical variables compared using Chi-square test or Fisher’s exact test
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Environmental Health

ISSN: 1476-069X