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Table 4 Odds ratios (OR) of amyotrophic lateral sclerosis associated with current proximity to any agricultural land or specific crop type within 100 m from residence (A), and with 20% continuous increase of any agricultural land or specific crop type (B)a

From: Pesticide exposure assessed through agricultural crop proximity and risk of amyotrophic lateral sclerosis

 

Cases

Controls

Total (N = 3440)

Cases

Controls

Emilia-Romagna (N = 2434)

Cases

Controls

Sicily (N = 1006)

Crops

Exp/Unexp

Exp/Unexp

OR

(95% CI)

Exp/Unexp

Exp/Unexp

OR

(95% CI)

Exp/Unexp

Exp/Unexp

OR

(95% CI)

(A)

 Total agricultural land

290/413

1184/1553

0.92

(0.78, 1.09)

205/294

858/1077

0.88

(0.72, 1.07)

85/119

326/476

1.04

(0.76, 1.42)

 Vineyards

27/676

91/2646

1.16

(0.75, 1.80)

25/474

88/1847

1.11

(0.70, 1.75)

2/202

3/799

2.64

(0.44, 15.89)

 Orchards

46/657

181/2556

0.99

(0.71, 1.38)

9/490

97/1838

0.35

(0.17, 0.69)

37/167

84/718

1.89

(1.24, 2.89)

 Arable crops

203/500

826/1911

0.94

(0.78, 1.13)

191/308

756/1179

0.97

(0.79, 1.18)

12/192

70/732

0.65

(0.35, 1.23)

 Vegetable crops

3/700

5/2732

2.35

(0.56, 9.82)

2/497

4/1931

1.94

(0.35, 10.64)

1/203

1/801

3.95

(0.25, 63.36)

 Olive groves

        

6/198

11/791

2.18

(0.80, 5.96)

(B)

 Total agricultural land

  

1.01

(0.94, 1.09)

  

0.96

(0.88, 1.04)

  

1.35

(1.13, 1.63)

 Vineyards

  

1.15

(0.86, 1.54)

  

1.12

(0.83, 1.51)

  

Too high

 Orchards

  

0.93

(0.70, 1.24)

  

0.12

(0.02, 0.82)

  

1.52

(1.08, 2.13)

 Arable crops

  

0.98

(0.89, 1.08)

  

0.98

(0.89, 1.08)

  

1.01

(0.63, 1.61)

 Vegetable crops

  

4.00

(0.25, 63.9)

  

4.00

(0.25, 63.95)

  

-

 

 Olive groves

          

5.01

(1.05, 23.97)

  1. aResults for dichotomous analysis expressed as crude OR for matched sets, and for continuous analysis using a conditional logistic regression model. Some estimates could not be computed because of too few exposed subjects