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Table 5 Odds ratio (OR) of amyotrophic lateral sclerosis for current proximity to agricultural fields in tertiles of current exposurea

From: Pesticide exposure assessed through agricultural crop proximity and risk of amyotrophic lateral sclerosis

 

Total

Emilia-Romagna

Sicily

 

I

II

III

I

II

III

I

II

III

Total agricultural land

 Cut off (%)

<12.2

12.2-38.8

>38.8

<17.2

17.2-44.6

>44.6

<6.3

6.3-21.6

>21.6

 Cases/Controls

487/1949

113/394

103/394

354/1363

80/286

65/286

138/586

25/108

41/108

 OR (95% CI)

1.00

1.15

(0.91, 1.45)

1.04

(0.82, 1.33)

1.00

1.08

(0.82, 1.43)

0.88

(0.65, 1.18)

1.00

0.97

(0.60, 1.57)

1.57

(1.06, 2.34)

Vineyards

 Cut off (%)

<9.7

9.7-31.1

>31.1

<9.8

9.8-31.5

>31.5

<2.8

2.8-9.4

>9.4

 Cases/Controls

683/2677

11/30

9/30

480/1877

11/29

8/29

203/800

0/1

1/1

 OR (95% CI)

1.00

1.46

(0.72, 2.95)

1.19

(0.55, 2.54)

1.00

1.51

(0.74, 3.07)

1.10

(0.49, 2.44)

1.00

-

 

3.47

(0.22, 55.83)

Orchards

 Cut off (%)

<7.8

7.8-26.4

>26.4

<9.6

9.6-28.9

>28.9

<7.5

7.5-23.4

>23.4

 Cases/Controls

675/2618

15/59

13/60

497/1871

1/33

1/31

179/746

12/29

13/27

 OR (95% CI)

1.00

0.98

(0.55, 1.74)

0.85

(0.46, 1.57)

1.00

0.11

(0.02, 0.82)

0.11

(0.02, 0.84)

1.00

1.74

(0.86, 3.49)

1.94

(1.00, 3.77)

Arable crops

 Cut off (%)

<13.1

13.1-38.7

>38.7

<14.9

14.9-40.9

>40.9

<3.9

3.9-17.1

>17.1

 Cases/Controls

551/2187

89/275

63/275

359/1431

82/252

58/252

196/756

2/23

6/23

 OR (95% CI)

1.00

1.29

(0.99, 1.69)

0.91

(0.68, 1.22)

1.00

1.31

(0.99, 1.73)

0.91

(0.67, 1.24)

1.00

0.35

(0.08, 1.48)

1.01

(0.40, 2.54)

Vegetable crops

 Cut off (%)

<6.4

6.4-20.9

>20.9

<8.1

8.1-20.9

>20.9

<4.8

-

>4.8

 Cases/Controls

701/2734

1/2

1/1

498/1933

0/1

1/1

203/801

0/0

1/1

 OR (95% CI)

1.00

1.81

(0.16, 20.08)

4.00

(0.25, 63.95)

1.00

-

 

4.00

(0.25, 63.95)

1.00

-

 

3.46

(0.22, 55.78)

Olive groves

 Cut off (%)

          

<2.9

2.9-9.1

>9.1

 Cases/Controls

          

199/795

0/4

5/3

 OR (95% CI)

          

1.00

-

 

6.44

(1.54, 26.98)

  1. aTertile cutpoints based on exposure of subjects having proximity to crops >0, with subjects having exposure = 0 included in the bottom tertile. OR computed using a conditional logistic regression model. Some estimates could not be computed because of too few exposed subjects