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Fig. 1 | Environmental Health

Fig. 1

From: Genomic characterization of chronic lymphocytic leukemia (CLL) in radiation-exposed Chornobyl cleanup workers

Fig. 1

Genomic landscape of CLL cases. (a) Prevalence of driver mutations, as defined in Landau et al. [23] in Western-CLL (dbGaP/Western; W-CLL cases from previous sequencing studies, light gray bars), Chornobyl cleanup workers with CLL (Exposed; UR-CLL, black bars) and unexposed Ukrainian CLL cases (UnExpsed; UN-CLL, gray bars). The asterisks identify significant comparisons (p < 0.05); (b) Tiling plot of predicted damaging mutations in exposed (UR-CLL) and unexposed (UN-CLL) Ukrainian patients. Horizontal rows depict mutations in a particular gene and functional category, and vertical columns represent individual patients (exposed and unexposed). Patients without mutations were excluded from the figure. Mutations are shaded according to their mutant allele fraction (MAF)

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