From: Prenatal exposure to phthalates and autism spectrum disorder in the MARBLES study
 | ASD versus TD | Non-TD versus TD | ||
---|---|---|---|---|
RRR a | 95% CI | RRR a | 95% CI | |
Average exposure during the 2nd and 3rd trimesters (n = 201; TD = 100, ASD = 46, Non-TD = 55) | ||||
MEP | 1.23 | (0.81, 1.85) | 1.38 | (1.01, 1.90)* |
MiBP | 0.64 | (0.37, 1.12) | 1.18 | (0.72, 1.94) |
MHiBP | 0.64 | (0.35, 1.19) | 1.10 | (0.64, 1.90) |
MBP | 0.87 | (0.45, 1.69) | 1.48 | (0.86, 2.53) |
MHBP | 0.91 | (0.44, 1.89) | 1.35 | (0.77, 2.37) |
MBzP | 0.83 | (0.53, 1.31) | 1.31 | (0.90, 1.90) |
MCPP | 0.71 | (0.47, 1.06) | 1.43 | (0.95, 2.14)# |
MCOP | 0.76 | (0.53, 1.11) | 1.29 | (0.89, 1.87) |
MCNP | 0.92 | (0.61, 1.39) | 1.38 | (0.96, 1.97)# |
ΣDEHP b | 0.75 | (0.43, 1.32) | 1.36 | (0.88, 2.08) |
Analysis restricted to samples collected during the 2nd trimester (n = 134; TD = 66, ASD = 29, Non-TD = 39) | ||||
MEP | 0.95 | (0.61, 1.47) | 1.34 | (0.85, 2.10) |
MiBP | 0.53 | (0.23, 1.19) | 0.81 | (0.40, 1.60) |
MHiBP | 0.56 | (0.25, 1.21) | 0.72 | (0.33, 1.53) |
MBP | 0.48 | (0.19, 1.16) | 0.81 | (0.42, 1.56) |
MHBP | 0.54 | (0.24, 1.21) | 0.82 | (0.42, 1.59) |
MBzP | 0.75 | (0.42, 1.32) | 1.31 | (0.79, 2.15) |
MCPP | 0.53 | (0.32, 0.87)* | 1.31 | (0.83, 2.07) |
MCOP | 0.68 | (0.46, 1.00) | 1.21 | (0.77, 1.87) |
MCNP | 0.79 | (0.49, 1.25) | 1.24 | (0.80, 1.91) |
ΣDEHP b | 0.81 | (0.45, 1.42) | 1.14 | (0.71, 1.82) |
Analysis restricted to samples collected during the 3rd trimester (n = 190; TD = 97, ASD = 43, Non-TD = 50) | ||||
MEP | 1.30 | (0.84, 1.98) | 1.27 | (0.92, 1.72) |
MiBP | 0.60 | (0.33, 1.08) | 1.21 | (0.73, 1.98) |
MHiBP | 0.60 | (0.32, 1.10) | 1.10 | (0.63, 1.92) |
MBP | 1.11 | (0.55, 2.21) | 1.54 | (0.93, 2.55) |
MHBP | 1.32 | (0.67, 2.59) | 1.52 | (0.88, 2.60) |
MBzP | 0.94 | (0.61, 1.43) | 1.33 | (0.92, 1.92) |
MCPP | 0.86 | (0.58, 1.28) | 1.17 | (0.80, 1.69) |
MCOP | 0.85 | (0.59, 1.20) | 1.01 | (0.71, 1.42) |
MCNP | 0.90 | (0.59, 1.35) | 1.19 | (0.82, 1.70) |
ΣDEHP b | 0.83 | (0.44, 1.54) | 1.28 | (0.83, 1.94) |