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Table 1 Characteristics of children in Bangladeshi prospective cohort who provided serum antibody samples at age 5 years

From: Evaluating the effects between metal mixtures and serum vaccine antibody concentrations in children: a prospective birth cohort study

Variable

 

Child sex

Overall

Males

Females

 

N = 502

(n = 255)

(n = 246)

p-value

Maternal Education, n (%)

 illiterate

52 (10.4%)

29 (11.4%)

23 (9.3%)

0.76

 primary

187 (37.3%)

94 (36.9%)

93 (37.8%)

 

  ≥ secondary

262 (52.2%)

132 (51.8%)

130 (52.8%)

 

Total duration of breastfeeding, median (IQR), months

24.0 (19.0, 36.0)

24.0 (18.0, 36.0)

24.0 (24.0, 36.0)

0.41

WFA

−1.3 (−2.0, − 0.6)

− 1.2 (− 1.9, − 0.6)

− 1.5 (− 2.1, − 0.8)

0.005

Antibody concentration at age 5, median (IQR), IU/mL

 Diphtheria

0.06 (0.03, 0.12)

0.06 (0.03, 0.13)

0.06 (0.03, 0.12)

0.78

 Tetanus

0.21 (0.09, 0.40)

0.22 (0.10, 0.42)

0.20 (0.09, 0.37)

0.12

Arsenic (W-As), median (IQR), μg/L

 pregnancy

3.2 (1.2, 23.7)

3.2 (1.2, 24.2)

3.3 (1.2, 22.3)

0.70

 toddlerhood

7.1 (0.8, 47.7)

7.9 (0.9, 47.7)

6.9 (0.7, 49.4)

0.41

 childhood

2.7 (0.4, 38.4)

3.6 (0.4, 37.2)

2.5 (0.4, 39.1)

0.31

Manganese (W-Mn), median (IQR), μg/L

 pregnancy

565.0 (344.8, 796.0)

565.0 (350.5, 789.0)

569.5 (340.0, 814.0)

0.62

 toddlerhood

741.0 (322.5, 1478.5)

776.5 (358.0, 1560.0)

710.0 (308.0, 1410.0)

0.38

 childhood

748.6 (304.3, 1483.7)

721.3 (322.1, 1512.0)

806.5 (252.6, 1422.6)

0.91

Lead (B-Pb), median (IQR), μg/dL

 pregnancy

3.1 (1.6, 5.6)

3.2 (1.5, 5.2)

3.0 (1.6, 5.8)

0.78

 toddlerhood

6.4 (4.3, 10.0)

6.5 (4.4, 9.5)

6.0 (4.0, 10.4)

0.77

 childhood

4.7 (2.3, 7.0)

5.0 (2.9, 7.9)

4.6 (2.3, 6.5)

0.05

  1. Note: p-values Pearson chi-squared or Kruskal-Wallis rank sum differences in distribution of variable between sexes; IQR interquartile range (25th, 75th percentiles); IU international units; W- drinking water; WFA weight-for-age z-score