Persistent organic pollutants, pre-pregnancy use of combined oral contraceptives, age, and time-to-pregnancy in the SELMA cohort

Table 3 Weighted quantile sum index stratified according to age and use of combined oral contraceptives (COCs). Data presented are estimate (SE) and OR (95% CI)

Group		Outcome: TTP^a Estimate (SE)^b	Chemicals of concern^c	Outcome: Infertility OR (95% CI) ^b	Chemicals of concern^c
< 29 years old	Non-COC user	−0.02(0.05)	–	0.97 (0.22–4.26)	–
< 29 years old	COC user	0.03 (0.03)	–	0.92 (0.35–2.41)	–
≥ 29 years old	Non-COC user	0.09 (0.03)*	PCB 183, 156, 187, 118	1.79 (1.03–3.11)*	PCB 187, 156, 74, 183, transnonachlor
≥ 29 years old	COC user	0.07 (0.04)	–	1.27 (0.07–2.3)	–

^alog transformed + 1
^bAdjusted with parity, regularity of menses, maternal BMI, and smoking
^cChemicals with weight greater than 7.6%
* p < 0.05
Abbreviations: CI confidence interval, COCs combined oral contraceptives, PCB polychlorobiphenyl, OR odds ratio, SE standard error, TTP time-to-pregnancy

ISSN: 1476-069X