From: Airborne Benzo[a]Pyrene may contribute to divergent Pheno-Endotypes in children
Main exposure | Main Health Outcome groups of interest | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Non-atopic Children | Atopic Children | |||||||||
(A). | Control (Reference) | Asthmatics | Control (Reference) | Asthmatics | ||||||
N | N | N | N | |||||||
OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | |||||||
P-value | P-value | P-value | P-value | |||||||
Male | one ln-unit B[a]P | N = 63 | N = 20 | N = 8 | N = 55 | |||||
1 | 4.7 (1.9―11.5) | 1 | 2.0 (0.4―11.1) | |||||||
P = 0.001 | P = 0.331 | |||||||||
Female | one ln-unit B[a]P | N = 58 | N = 1 | N = 6 | N = 34 | |||||
1 | 44.8 (4.7―428.2) | 1 | 3.0 (0.7―12.7) | |||||||
P = 0.001 | P = 0.173 | |||||||||
(B). | Lean Control (Reference) | OV/OB Control | Lean Asthmatics | OV/OB Asthmatics | Lean Control (reference) | OV/OB Control | Lean Asthmatics | OV/OB Asthmatics | ||
N | N | N | N | N | N | N | N | |||
OR (95% CI) | OR (95% CI)c | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | |||
P-value | P-value | P-value | P-value | P-value | P-value | P-value | P-value | |||
Male | one ln-unit B[a]P | N = 56 | N = 7 | N = 17 | N = 3 | N = 7 | N = 1 | N = 43 | N = 12 | |
1 | 0.3 (0.1―1.0) | 9.6 (2.9―32.1) | 0.3 (0.1―2.1) | 1 | 0.4 (0.0―173.1) | 1.6 (0.3―9.7) | 2.2 (0.3―14.9) | |||
P = 0.054 | P < 0.001 | P = 0.247 | P = 0.786 | P = 0.594 | P = 0.409 | |||||
Female | one ln-unit B[a]P | N = 55 | N = 3 | N = 11 | N = 6 | N = 5 | N = 1 | N = 23 | N = 11 | |
1 | 0.3 (0.0―2.9) | 27.4 (3.2―237.1) | 46.1 (1.7―1271.4) | 1 | 0.0 (0.0―0.0) | 3.6 (0.6―23.3) | 17.1 (1.8―165.6) | |||
P = 0.286 | P = 0.003 | P = 0.024 | P = 0.998 | P = 0.173 | P = 0.014 |