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Table 2 Estimated base pair change in telomere length for a doubling of PFAS concentration

From: Associations between polyfluoroalkyl substance and organophosphate flame retardant exposures and telomere length in a cohort of women firefighters and office workers in San Francisco

 

Full Cohort Δbpc (CId)

Firefighters Δbp (CI)

Office Workers Δbp (CI)

PFHxS

 Model 1a

103 (−16,223)

72 (−92,235)

88 (−98,275)

 Model 2b

84 (− 35,202)

91 (−69,252)

69 (−116,254)

PFOA

 Model 1

273 (54,493)*

395 (85,705)*

175 (−135,485)

 Model 2

240 (25,455)*

329 (13,645)*

165 (−140,470)

PFOS

 Model 1

183 (15,352)*

304 (33,576)*

91 (− 125,308)

 Model 2

172 (5340)*

272 (− 4548)

124 (−95,342)

PFNA

 Model 1

126 (−60,312)

103 (− 144,350)

65 (− 233,362)

 Model 2

68 (−117,253)

52 (−195,299)

116 (−183,416)

PFDA

 Model 1

137 (−27,302)

300 (16,585)*

34 (−170,239)

 Model 2

104 (−58,266)

255 (−31,541)

60 (−148,267)

PFUnDA

 Model 1

26 (−55,106)

79 (−50,209)

−31 (−136,75)

 Model 2

13 (−67,93)

61 (−67,190)

2 (−114,117)

PFBuS

 Model 1

10 (−72,92)

−33 (− 151,84)

50 (−67,168)

 Model 2

23 (−58,104)

−4 (−123,114)

46 (− 72,165)

  1. a Model 1 adjusted for age (years)
  2. b Model 2 adjusted for age (years), dairy and egg consumption (times per week), and occupation (in full group only)
  3. c change in base pairs
  4. d CI = 95% confidence interval
  5. * statistically significant (p ≤ 0.05)