Long-term personal air pollution exposure and risk for acute exacerbation of idiopathic pulmonary fibrosis

Table 3 Long-term personal exposure to concentrations of air pollutants and risk of AE-IPF. Results reported from logistic regression models: Odds Ratio (OR) & 95% C.I., after adjusting for gender, age, smoking habits, recent FVC, recent DLCO and antifibrotic therapy. ^a also adjusting for telomere length ratio; ^b Ο3: also adjusting for PM_2.5

Results reported per (10 μg/m³):	All patients		Patients residing in the Greater Athens Area (n = 66)		Patients residing out of the Greater Athens Area (n = 52)
Results reported per (10 μg/m³):	OR (95% CI)	p-value	OR (95% CI)	p-value	OR (95% CI)	p-value
¹O₃	0.60 (0.43 to 0.86)	0.005**	0.57 (0.27 to 1.17)	0.126	0.76 (0.28 to 2.06)	0.590
^{a 2}O₃	0.27 (0.07 to 1.00)	0.050
^{b 1}O₃	0.55 (0.27 to 1.13)	0.105	0.42 (0.10 to 1.81)	0.245	0.78 (0.27 to 2.29)	0.654
^{b 2}O₃	0.26 (0.01 to 1.05)	0.052
¹NO₂	1.52 (1.15 to 2.00)	0.003**	1.58 (0.88 to 2.87)	0.128	3.89 (0.75 to 20.3)	0.106
^{a 2}NO₂	2.64 (0.99 to 7.05)	0.053
¹PM_2.5	2.21 (1.16 to 4.20)	0.016*	2.01 (0.56 to 7.12)	0.282	1.67 (0.08 to 36.5)	0.743
^{a 2}PM_2.5	2.78 (0.35 to 22.2)	0.335
¹PM₁₀	2.18 (1.15 to 4.15)	0.017*	1.96 (0.57 to 6.71)	0.285	1.93 (0.12 to 29.9)	0.637
^{a 2}PM₁₀	2.35 (0.31 to 17.9)	0.410

Abbreviations: FVC Forced Vital Capacity, DLCO Diffusing Capacity of the lung for carbon monoxide, O₃ ozone, PM particulate matter, NO₂ nitrogen dioxide
¹All patients (n = 118)
²All patients with telomere length ratio measurements (n = 36)
^* statistically significant at a = 5%
^** statistically significant at a = 1%

ISSN: 1476-069X