Conditions assessed | Studies included | Random effects model [95% CI] Generic invariance method | Heterogeneity (I2) | Egger’s test p-value | Random effects model [95% CI] Weighted per sample size |
---|---|---|---|---|---|
Prenatal PFOA and BMI in both sexes 0–3 years | -0.0140 [-0.0351; 0.0070] | 0.77 | 0.910 | -0.0133 [-0.0343; 0.0078] | |
4–18 years | 0.0000 [-0.0008; 0.0009] | 0.24 | 0.047 | 0.0275 [0.0059; 0.0491] | |
Prenatal PFOA and BMI in boys 0–3 years | -0.0022 [-0.0070; 0.0026] | 0.19 | 0.533 | -0.0051 [-0.0182; 0.0079] | |
4–18 years | 0.0000 [-0.0009; 0.0008] | 0.00 | 0.039 | -0.0115 [-0.0398; 0.0168] | |
Prenatal PFOA and BMI in girls 0–3 years | -0.0036 [-0.0413; 0.0341] | 0.87 | 0.673 | -0.0087 [-0.0313; 0.0139] | |
4–18 years | 0.0000 [-0.0001; 0.0002] | 0.23 | 0.672 | 0.0115 [-0.0084; 0.0313] | |
Prenatal PFOS and BMI in both sexes 0–3 years | -0.0101 [-0.0189; -0.0013] | 0.38 | 0.965 | -0.0092 [-0.0210; 0.0026] | |
4–18 years | 0.0002 [-0.0009; 0.0014] | 0.42 | 0.251 | 0.0008 [-0.0056; 0.0072] | |
Prenatal PFOS and BMI in boys 0–3 years | -0.0024 [-0.0071; 0.0024] | 0.21 | 0.123 | -0.0060 [-0.0128; 0.0007] | |
4–18 years | 0.0002 [-0.0029; 0.0033] | 0.00 | 0.538 | -0.0026 [-0.0128; 0.0077] | |
Prenatal PFOS and BMI in girls 0–3 years | -0.0065 [-0.0186; 0.0056] | 0.78 | 0.356 | -0.0086 [-0.0198; 0.0026] | |
4–18 years | -0.0006 [-0.0033; 0.0021] | 0.56 | 0.883 | 0.0065 [-0.0019; 0.0150] | |
Prenatal PFHxS and BMI in both sexes 4–18 years | 0.0000 [-0.0071; 0.0071] | 0.00 | 0.435 | -0.0009 [-0.0600; 0.0582] | |
Prenatal PFHxS and BMI in boys 0–3 years | -0.0023 [-0.0054; 0.0009] | 0.00 | 0.659 | 0.0159 [-0.0998; 0.1317] | |
4–18 years | 0.0040 [-0.0108; 0.0188] | 0.00 | 0.051 | -0.0694 [-0.1534; 0.0146] | |
Prenatal PFHxS and BMI in girls 0–3 years | 0.0343 [-0.0360; 0.1046] | 0.33 | 0.463 | 0.0806 [-0.0197; 0.181] | |
4–18 years | -0.0014 [-0.0050; 0.0021] | 0.00 | 0.387 | 0.0221 [-0.0348; 0.0790] | |
Prenatal PFNA and BMI in both sexes 4–18 years | -0.0001 [-0.0033; 0.0030] | 0.00 | 0.072 | 0.0656 [-0.0252; 0.1564] | |
Prenatal PFNA and BMI in boys 0–3 years | -0.0083 [-0.0183; 0.0016] | 0.00 | 0.831 | 0.0009 [-0.0495; 0.0513] | |
4–18 years | 0.0022 [-0.0052; 0.0097] | 0.17 | 0.120 | 0.1851 [0.0280; 0.3421] | |
Prenatal PFNA and BMI in girls 0–3 years | 0.0216 [-0.0031; 0.0463] | 0.52 | 0.119 | 0.0588 [-0.0023; 0.1198] | |
4–18 years | -0.0002 [-0.0027; 0.0023] | 0.05 | 0.290 | 0.0976 [-0.0355; 0.2307] | |
Prenatal PFDA and BMI in both sexes 4–18 years | -0.0007 [-0.003; 0.0015] | 0.00 | 0.001 | -0.0816 [-0.2605; 0.0973] | |
Prenatal PFDA and BMI in boys 0–3 years | -0.0069 [-0.0286; 0.0147] | 0.00 | 0.196 | 0.0365 [-0.0673; 0.1402] | |
4–18 years | 0.0016 [-0.0038; 0.0070] | 0.00 | 0.410 | -0.0111 [-0.3852; 0.3630] | |
Prenatal PFDA and BMI in girls 0–3 years | 0.0111 [-0.0205; 0.0427] | 0.41 | 0.407 | 0.1055 [-0.0437; 0.2546] | |
4–18 years | -0.0017 [-0.0077; 0.0043] | 0.00 | 0.829 | -0.1628 [-0.4729; 0.1474] | |
Prenatal PFUA and BMI in both sexes 4–18 years | -0.0015 [-0.0048; 0.0017] | 0.00 | 0.749 | -0.3931 [-1.2412; 0.4549] | |
Prenatal PFUA and BMI in boys 4–18 years | 0.0021 [-0.0055; 0.0098] | 0.00 | 0.263 | 0.2827 [-0.2755; 0.8409] | |
Prenatal PFUA and BMI in girls 4–18 years | -0.0045 [-0.0098; 0.0008] | 0.00 | 0.325 | -0.0501 [-0.4704; 0.3701] | |
Prenatal PFOA and risk of overweight 4–18 years | 0.0084 [-0.0003; 0.0171] | 0.02 | 0.063 | 0.0142 [-0.0006; 0.0289] | |
Prenatal PFOS and risk of overweight 4–18 years | 0.0007 [-0.0012; 0.0026] | 0.19 | 0.504 | 0.0016 [-0.0018; 0.0050] | |
Prenatal PFHxS and risk of overweight 4–18 years | -0.0035 [-0.0235; 0.0166] | 0.41 | 0.312 | -0.0627 [-0.1201; -0.0052] | |
Prenatal PFNA and risk of overweight 4–18 years | 0.025 [-0.0116; 0.0616] | 0.02 | 0.338 | -0.0633 [-0.1611; 0.0344] | |
Prenatal PFOA and WC in both sexes 4–18 years | 0.0000 [-0.0001; 0.0000] | 0.00 | 0.232 | 0.0007 [-0.0171; 0.0184] | |
Prenatal PFOA and WC in boys 4–18 years | -0.0001 [-0.0002; 0.0001] | 0.00 | 0.199 | -0.0023 [-0.0218; 0.0173] | |
Prenatal PFOA and WC in girls 4–18 years | 0.0000 [-0.0001; 0.0001] | 0.43 | 0.939 | -0.0040 [-0.0194; 0.0114] | |
Prenatal PFOS and WC in both sexes 4–18 years | 0.0000 [0.0000; 0.0001] | 0.00 | 0.675 | -0.0038 [-0.0115; 0.0039] | |
Prenatal PFOS and WC in boys 4–18 years | 0.0000 [-0.0001; 0.0001] | 0.00 | 0.492 | -0.0012 [-0.0093; 0.0068] | |
Prenatal PFOS and WC in girls 4–18 years | -0.0001 [-0.0004; 0.0003] | 0.51 | 0.631 | 0.0015 [-0.0053; 0.0083] | |
Prenatal PFHxS and WC in both sexes 4–18 years | 0.0003 [-0.0014; 0.0020] | 0.13 | 0.621 | -0.0069 [-0.0420; 0.0281] | |
Prenatal PFHxS and WC in boys 4–18 years | -0.0001 [-0.0041; 0.0039] | 0.19 | 0.726 | -0.0518 [-0.1069; 0.0032] | |
Prenatal PFHxS and WC in girls 4–18 years | 0.0000 [-0.0004; 0.0005] | 0.06 | 0.675 | 0.0144 [-0.0285; 0.0572] | |
Prenatal PFNA and WC in both sexes 4–18 years | 0.0004 [-0.0006; 0.0015] | 0.14 | 0.051 | 0.0411 [-0.0002; 0.0824] | |
Prenatal PFNA and WC in boys 4–18 years | -0.0001 [-0.0006; 0.0003] | 0.00 | 0.070 | 0.0477 [-0.0105; 0.1059] | |
Prenatal PFNA and WC in girls 4–18 years | 0.0010 [-0.0002; 0.0023] | 0.00 | 0.779 | -0.0035 [-0.0509; 0.0438] | |
Prenatal PFDA and WC in both sexes 4–18 years | 0.0003 [-0.0002; 0.0008] | 0.00 | 0.956 | 0.0324 [-0.1791; 0.2438] | |
Prenatal PFDA and WC in boys 4–18 years | -0.0001 [-0.0004; 0.0003] | 0.00 | 0.738 | 0.0312 [-0.3097; 0.3721] | |
Prenatal PFDA and WC in girls 4–18 years | 0.0010 [-0.0001; 0.0021] | 0.00 | 0.963 | 0.0329 [-0.2441; 0.3100] | |
Prenatal PFUA and WC in both sexes 4–18 years | 0.0005 [-0.0010; 0.0020] | 0.67 | 0.345 | 0.3729 [0.0703; 0.6755] | |
Prenatal PFUA and WC in boys 4–18 years | 0.0002 [-0.0044; 0.0049] | 0.38 | 0.195 | 0.5132 [-0.1139; 1.1404] | |
Prenatal PFUA and WC in girls 4–18 years | 0.0015 [-0.0015; 0.0045] | 0.00 | 0.242 | 0.2805 [-0.1624; 0.7234] | |
Childhood PFOA and BMI in both sexes 4–18 years | -0.0525 [-0.1039; -0.0012] | 0.84 | 0.023 | -0.0445 [-0.0604; -0.0286] | |
Childhood PFOA and BMI in boys 4–18 years | -0.0910 [-0.2488; 0.0668] | 0.89 | 0.394 | -0.0410 [-0.2285; 0.1464] | |
Childhood PFOA and BMI in girls 4–18 years | -0.0150 [-0.0401; 0.0100] | 0.74 | 0.256 | -0.0134 [-0.0456; 0.0187] | |
Childhood PFOS and BMI in both sexes 4–18 years | -0.0166 [-0.0283; -0.0049] | 0.82 | 0.011 | -0.0226 [-0.0412; -0.0039] | |
Childhood PFOS and BMI in boys 4–18 years | -0.0229 [-0.0338; -0.0120] | 0.00 | 0.359 | -0.0235 [-0.0354; -0.0116] | |
Childhood PFOS and BMI in girls 4–18 years | -0.0162 [-0.0531; 0.0207] | 0.84 | 0.972 | -0.0278 [-0.0719; 0.0164] | |
Childhood PFHxS and BMI in both sexes 4–18 years | -0.0247 [-0.0814; 0.0320] | 0.35 | 0.260 | -0.0334 [-0.1157; 0.0489] | |
Childhood PFHxS and BMI in boys 4–18 years | -0.0547 [-0.2558; 0.1464] | 0.18 | 0.444 | -0.0331 [-0.1620; 0.0957] | |
Childhood PFHxS and BMI in girls 4–18 years | 0.0667 [-0.1136; 0.2469] | 0.35 | 0.079 | 0.0399 [-0.1249; 0.2047] | |
Childhood PFNA and BMI in both sexes 4–18 years | -0.2162 [-0.4883; 0.0558] | 0.81 | 0.383 | -0.3279 [-0.6121; -0.0438] | |
Childhood PFOA and risk of overweight in both sexes 4–18 years | -0.0101 [-0.0497; 0.0295] | 0.84 | 0.413 | -0.0074 [-0.0554; 0.0407] | |
Childhood PFOS and risk of overweight in both sexes 4–18 years | 0.0016 [-0.0081; 0.0113] | 0.78 | 0.231 | -0.0007 [-0.0137; 0.0123] |